There is no guidebook to science... Bateson

"In the nature of the case, an explorer can never know what he is exploring until it has been explored. He carries no Baedeker in his pocket, no guidebook which will tell him which churches he should visit or at which hotels he should stay. He has only the ambiguous folklore of others who have passed that way. No doubt deeper levels of the mind guide the scientist or the artist toward experiences and thoughts which are relevant to those problems which are somehow his, and this guidance seems to operate long before the scientist has any conscious knowlwdge of his goals. But how this happens we do not know"

Gregory Bateson - Steps to an Ecology of Mind